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                    κȫ방֢롱

                          ӡ

    żѧˡ20042ڽܵԺʿκȫƪ£
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    ǣκԺʿձڼķ¼Ӣܹ4ƪ

Wei YQ, Zhao X, Kariya Y, Fukata H, Teshigawara K, Uchida A.
Induction of apoptosis by quercetin: involvement of heat shock protein.
Cancer Res. 1994 Sep 15;54(18):4952-7. 
Wei YQ, Zhao X, Kariya Y, Teshigawara K, Uchida A.
Inhibition of proliferation and induction of apoptosis by abrogation of 
heat-shock protein (HSP) 70 expression in tumor cells.
Cancer Immunol Immunother. 1995 Feb;40(2):73-8. 
Zhao X, Wei YQ, Kariya Y, Teshigawara K, Uchida A. 
Accumulation of gamma/delta T cells in human dysgerminoma and seminoma: 
roles in autologous tumor killing and granuloma formation.
Immunol Invest. 1995 May;24(4):607-18. 
Wei Y, Zhao X, Kariya Y, Fukata H, Teshigawara K, Uchida A.
Induction of autologous tumor killing by heat treatment of fresh human tumor cells: 
involvement of gamma delta T cells and heat shock protein 70.
Cancer Res. 1996 Mar 1;56(5):1104-10. 

    ֪ʣµ38ƪ£ǸУҲPubMed
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κȫ방֢롱	
[2004-02-23]

2004꡶ѧˡ2ڷ----κȫ

/  ־

20031125磬κȫڱѡΪйѧԺԺʿϢĴ
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Ӵˣκȫ޷˵ѡԼоѧ̽Ѱ
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ҪЩǿĶ. 57ƪȷʵе(2001-2005 Nature Medicine
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ȻκȫûֱӴǻ֪һġκȫ91ǰ
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κȫձعһͿԽסԺҽҽʦҽʦѵ
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ʵĲ֪Σ

һò˲֪飬һ˷ˣǷŭˣ˾
εģϲģġһ뵽ˣΪκԺʿġ

(XYS20060408)

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ӡͶ⣡

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ϸΪԴκ2000ǰ2000ҲУ˵˵
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ͬԴԵײĿʶףҲFACS,ELISA֤Ϊʲ
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Ϊͨڴ󵰰׵ṹУҺϳɵrabbitϸĤ浰
ĶǶܵõrabbitĶ¡塣ҲκӦúNature Medicine
һεĻˣ˿˲ʵ˿ûˮƽһ档

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ע䵽СΪξûзӦأPNAS"Sera from mice immunized 
with XVEGF-p recognized not only recombinant Xenopus VEGF, but also mouse 
and human VEGF in Western blotting analysis", but " the number of anti-VEGF 
antibody-producing B cells was 76  28 per 105 mononuclear cells in 
the spleen of mice immunized with XVEGF-p, but was undetectable in 
mice immunized with MVEGF-p or c-p or in nonimmunized mice.

    ⻪"ҽԺ"Ծѳ,ҽ.Ҫ,
֪,һ֪ڱЩ˵Ǯö.û˵һ
һǮ,ϾͷʼһµʵҲ,豸Ҫ,
ʹ500KȫҲò.

(XYS20060408)

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Ҳ˵κȫ

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ʵܸӣȡںܶأϸ꣬
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κϸ۲쵽һĿԣͶ϶Ǹشͻơһ
ײ֪˼50кܶ౨ϡ档ɵ90
ȷVEGFRѪƤϸγ֮ĹϵҴҶ
ƣǳȡϵһǸС֮Ʋ⣬
ĺʱǵɲNature-Medicine
־ı༩ҲȫɵϣԳ岻⣬ҪΪȱٷˮƽ
֤ݡȻͺݺܺݵزһ£޻˵󲻾ͳɹ

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ԲμǵĶᣬΪǵı棬߿PDFͶӰ߸ǽ
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־˵ FolkmanѪŪòò㶪ڹְλһ٩
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(XYS20060408)

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Ҷйκȫʦ۵һ㿴

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(XYS20060408)

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ҽʷ˭ֹģ

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˵һ󹦡ôǵд汾ҲԱѧʽ1990ձ
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ҲΪд֤ʣϧͬһ(2001ڱΪ
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(XYS20060408)

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һò顪ʷֲġ֪ʶ֡



      ãѧٵΪҺܾ塣

      ע˿ĵĴ٣֪ûдģ

      ʱ䣬ΪѧϰҪڿʷֲġ֪ʶ֡廪ѧ档
ΣѧϰѹſⱾġƴյģдԵĴ
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עѧ

(XYS20060408)

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ӡ롰ѧ١޸׸ʺ



ӵռ˸µԣ
Ҳԭܶ˶ġ治

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һڶڲܼЧʱ򣬺ܶ˶ѡЩ
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ЩΪûãҲΪȻΪ䡰ѧ١Ȼα겻
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ҪлʱΪѧǸܵƽȵϢ
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200647 

(XYS20060408)

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Ϸĩı༭ǵ

ߣJingzhang2

Ϻֵ֪ͣϺ˴ʮһֱ㵥⣬
޷ֱӺȽϡǰ׹ζˣҲѧϺ
⡣

ϵѧѧԺڣõıñ׼ֵĹ㶫бȽϣ
͹ˡϷĩı༭Ӧǹ㶫İɣ㶫ʵ˽ʮ
׼ƶȣӦ֪ġ΢еӣӦý黻ʡݣ
ݡ

߿Ӧϳָ

Ϸĩ 2006-04-06 14:37:25

ǧ

ĿĿصĿôȫ˰ֵ֧Ĵѧ
ܷƽԭԼĹѧӦΪṩһ
ݣ赲ؿָߵѧøԽĽԴ

ꡰᡱڼ䣬ٴӳ˸߿еĵ⡣Ŀǰ
ƶȿ£߿¼ȡָ겻ֳͬ൱¼ȡ߲
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¼ȡĿ581֡628֣ȫ֮ͣ£㶫ʡ
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˵Ǳˡ׼ȷ˵ĸĸǱˣô
¼ȡ֪֮ͨܿĻ㣬ôע
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УձԼ޷ĻȻԿ˷
شӰ죬Ҳѹôȥԡ߿ˡʵ
ǵƶֱӵˡ߿񡱣ôʲôȨͷЩ
ġΪأ

߿ĵָ꼰ľ޴¼ȡ߲죬Ȼܷ
ܷ33Ĺ涨ڷǰһƽȡġɡ
ȻӦǵָȫ˴䳣ίƶĴдġɡָ
ƶľԼķɹ淶Ŀǰ󲿷ָУҪĹ
ѧУȾˡɫʣִеָ¼ȡ߹涨
ܷϵġɡΪӦص33涨ƽԭ÷ѧרҵ
˵ܷ33ڸУ¼ȡ߹涨ǡáġ

ôʲôǡƽȡأƽȱйʽƽȡ
ʾÿơ˶ӦƵĴǷʸĿ
Ǿ͸߿ԵĴǴƵġʵϣܷϸͬġ
˵ƽȡζŻ¼ȡƽȻᡣ¼ȡ
580¼ȡ860ôߵĻȻǲƽȵġ

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ƽṩܷܽܵɣôֲƽܷġˣؼ
ԴɾʲôǶȿƽȹʽһؼǡ
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ᡣԴܹǾͱʾͬȺġʵǲ
ͬġ

Կ϶ǣܹ¼ȡ߲ɡ
ΪĸǱĲؾͻý¼ȡߵȨ㶫
ҲӦҡ͵ٸߵżܷǰֲ
ȫģΪһġΪءĸݵ
ضκβͬȻܷǰƽȵģҲӦûø߿
¼ȡƽȻ᣻仰˵ǵ¼ȡӦȫͬġ

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˵ӵӦȻִܽҿɿվ
סŵġϾҽԴǼ޵ģӦ潻齻
ĶطȷʵԵظУṩ˲ϵ֧֣ôʵġ
ƺڰͬ׼¼ȡ⵱ѧѧѡѧ
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ǰãйѧУ󽫰ո˿ڱ
¼ȡָꡣΪ⽫Ǹ߿ƶȵһҪĸĽ塣
Ȼ˿Ϊ¼ȡָı׼Ƿһƽԭ˿ڶĵ
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ƶȣô¼ȡ߻ǽݱͿԤĲ졣
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ĵӡǵģȥ͸˿ڳɱġƽȡȻ
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ȻӺܷ33ƽԭִȻˣΪʲôɴȡ߿
ָƶأ

ԤһԷϳձǡСĿǰˡ
ϳָ꾿ǷأǲҪ֡СԼˡʵϸ
ƽ¼ȡƶڸУʵʩˡǵо¼ȡƶ
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